Database : HANSEN
Search on : RELACOES HOSPEDEIRO-PARASITA/IMUNOL [Subject descriptor]
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Id:18218
Author:Britton, Warwick J; Lockwood, Diana N. J
Title:Leprosy ..-
Source:s.l; s.n; 2004. 11 p. ilus, tab, graf.
Abstract:Leprosy remains an important health problem wordwide. The disease in caused by a chronic granulomatous infection of the skin and peripheral nerves with Mycobacterium leprae. The clinical range from tuberculoid to lepromatous leprosy is a result of variation in the cellular immune response to the mycobacterium. The resulting impairment of nerve fuinction causes be disabilities associated with leprosy. This review summarises recent advances in understanding of the biology of leprosy, clinical features of the disease, the current diagnostic criteria, and the new approaches to treatment of the infection and the immune-mediated complications. Supervesed multi-drug therapy (MDT) for fixed durations is highly effective for all forms of the disease. The widespread implemantation of MDT has been associated with a fall in the prevalence of the leprosy but as yet no reduction in the case-detection rate globally. Thus, leprosy control activities must be maintained for decades to interrupt transmission of infection (AU).
Descriptors:HANSENIASE/compl
HANSENIASE/diag
HANSENIASE/epidemiol
HANSENIASE/prev
HANSENIASE/terap
HANSENIASE/transm
MYCOBACTERIUM LEPRAE/quim
MYCOBACTERIUM LEPRAE/citol
MYCOBACTERIUM LEPRAE/imunol
MYCOBACTERIUM LEPRAE/patogen
QUIMIOTERAPIA COMBINADA
- NEURITE/etiol
 NEURITE/imunol
 NEURITE/microbiol
 EDUCACAO EM SAUDE/tend
 RELACOES HOSPEDEIRO-PARASITA/imunol
Limits:HUMANO
Location:BR191.1; 09193/s


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Id:11334
Author:Kirsztajn, G. M; Nishida, S. K; Silva, M. S; Lombardi, C; Ajzen, H; Pereira, A. B
Title:Specific and nonspecific aspects of humoral immune response in leprosy ..-
Source:s.l; s.n; 1994. 12 p. graf.
Descriptors:ADOLESCENCIA
ANTICORPOS ANTINUCLEARES
ANTICORPOS ANTIBACTÉRIAS
PROTEINA C-REATIVA
CRIANÇA
RELAÇOES HOSPEDEIRO-PARASITA
HANSENIASE
HANSENIASE
HANSENIASE LEPROMATOSA
HANSENIASE LEPROMATOSA
MYCOBACTERIUM LEPRAE
FATOR REUMATOIDE
SENSIBILIDADE E ESPECIFICIDADE
Location:BR191.1; 06946/s


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Id:10156
Author:Abel, Laurent; Sanchez, Fabio O; Oberti, Jean; Thuc, Nguyen V; Van Hoa, Le; Dap, Vu D; Skamene, Emil; Lagrange, Philippe H; Schurr, Erwin
Title:Susceptibility to leprosy is linked to the human NRAMP1 gene ..-
Source:s.l; s.n; 1998. 13 p. ilus, tab.
Descriptors:ALELOS
PROTEINAS DE TRANSPORTE
SUSCETIBILIDADE A DOENÇA
MARCADORES GENÉTICOS
HAPLOTIPOS
RELAÇOES HOSPEDEIRO-PARASITA
HANSENIASE
PROTEINAS DA MEMBRANA
LINHAGEM
POLIMORFISMO (GENÉTICA)
Location:BR191.1; 07069/s


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Id:9230
Author:Sampaio, Elizabeth P; Pereira, Geraldo M. B.; Pessolani, Maria Cristina V; Sarno, Euzenir Nunes
Title:Interaction of the leprosy bacillus and the human host: relevant components and mechanism of disease ..-
Source:s.l; s.n; 1994. 10 p. ilus, graf.
Descriptors:MYCOBACTERIUM LEPRAE
HANSENIASE
HANSENIASE
SISTEMA IMUNE
VIRULENCIA
SEQUENCIA DE BASES
LINFOCITOS T
RELAÇOES HOSPEDEIRO-PARASITA
Location:BR191.1; 06102/s


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